Corona virus ailment of 2019 (covid-19) has emerged as a worldwide fitness threat. Unfortunately, there are very limited authorized drugs to be had with mounted efficacy towards the sars-cov-2 virus and its inflammatory action. Vaccine improvement is actively being researched, however it is able to take over a year to grow had to standard public. Certain medicinal drugs, for example, dexamethasone, antimalarial (chloroquine/ hydroxychloroquine), antiviral (remdesivir), and interleukin-6 receptor blocking off monoclonal antibodies (tocilizumab), are utilized in diverse mixtures as off-label medicinal drugs for treatment of covid-19. Essential oils (EOs) have lengthy been recognized to have anti-inflammatory, immunomodulatory, bronchodilator, and antiviral activity and are being proposed to have action towards sarc-cov-2 virus. Owing to their lipophilic nature, Eos is recommended to penetrate viral membranes effortless lymain to membrane disruption. Moreover, Eos comprise more than one lively phytochemicals that can act synergistically on more than one ranges of viral replication and additionally induce high-quality results on host breathing gadget consisting of bronchodilator and mucus lyses. At present, most effective computer-aided docking and little in vitro research are to be had which display anti-sarc-cov-2sports of Eos.

The main cause of Protein Energy Malnutrition (PEM) is inadequate intake of food, both in quantity and quality.   According to Ayurveda, the drug or diet that reverses or break the Samprapti is ideal for the treatment of that particular disease. The drug can be used singly or in combination to achieve the prescribed objective. As underweight children are very common in a developing country like India, hence a nutrient rich single drug can be a useful tool for their treatment. Shigru or sahijan has the potential of providing all essential nutrients needed for the underweight child. Viewing this aspect it is the need of the hour to have in depth review of sahijan as wonder nutritious herb as described in ayurvedic texts and in modern science. The lucid survey of literature shows that Sahijan has a broad spectrum of pharmacological and therapeutic activities. It has diverse biological potentials and has a great scope for further new area of investigations.

: In the present scenario when both simple and life-threatening infectious diseases are increasingly becoming an attractive proposition, there is an urgent need for new treatments against the causative agents like bacteria, fungi and viruses. The aim of this review is to provide an overview of the various aspects of repurposing of a drug in comparison to the traditional drug production system. It will give a general view about the manufacturing process, present approaches, and opportunities used for the traditional drug processing and for drug repurposing.

Amaranthus species are mostly present as weeds and consumed as vegetables in Northern Sudan the present study was conducted to determine the proximate and phytochemical constituents of leaves, roots, and stems of A. blitum, A. viridis, A. spinosus, and A. graecizans using standard reference methods. Leaves of A. blitum recorded highest content of moisture (26%), total sugars (1.8 mg/g), reducing sugars (0.6 mg/g), lipids (14.24%), amino acids (1.5 mg/g), and pectic substances (32.67%). Highest leaves contents of starch (2.04 mg/g), crude fibers (9.71%), and ash (22.64%) were reported for A.graecizans highest record of protein was reported for A. spinosus leaves (0.13 mg/g) Highest amount of anthocycnin (12.4 mg/100g) was detected in the leaves of A.viridis Stem of A. blitum recorded highest content of reducing sugars amino acids and lipids Highest stem total sugars starch and pectic substances were recorded for A. spinosus. Highest amounts of root total sugars starch were recorded for A spinosus while highest contents of roots moisture crude fibers, ash, and pectic substances were recorded for A.viridis Amount of tannins in all parts of the studied species is in the safe range for human consumption. Studied species were recommended as available and accessible nutritious plants

The present study was conducted to screen α-amylase and α-glucosidase inhibitory activity of Sulfated heteropolysaccharides extracted from Hypnea valentiae and associated protective role on oxidative stress observed with diabetic complications. The IC50 of sulfated polysaccharide and standard Acarbose is found to be 191.7 µg/ml and 31.99 µg/ml against α-amylase. The IC50 of sulfated polysaccharide and standard Acarbose is found to be 151.0 µg/ml and 21.85 µg/ml against α-glucosidase respectively. The sulfated polysaccharide increased Glutathione peroxidase activity, an antioxidant enzyme in a dose dependent manner in L6 cells. The Extract showed decrease in H₂O₂ induced cytosolic ROS generation in L6 Cells measured using fluorescence dye 2’, 7’–dichlorofluorescein. Thus the sulfated polysaccharide exhibited dual role of delaying absorption of glucose via inhibition of α-amylase and α-glucosidase and attenuate oxidative stress by scavenging ROS & regulating glutathione antioxidant defense system. Hence we conclude that polysaccharide fraction precipitated from the extract ameliorates hyperglycemia and associated oxidative stress.

Rasashastra is a branch of Ayurveda which deals with preparation of different formulations like herbal, mineral, and Herbo-Mineral. All the formulations are having their own importance in treating many ailments. Treating Vaidya has to select the suitable formula by considering condition of the patient. Every medicine has got its own limitations to use in different ailments especially Rasoushadhis used in pregnancy condition and in paediatric care. There are many formulations given in rasa texts to manage pregnancy condition and Bala roga. In Ayurveda there is a detail description about the pregnant women and its care. During the 9 months of journey, a pregnant woman suffers from various ailments which are due to the state of being pregnant. To treat this condition many Herbo-mineral compounds are described in rasa Grantha, ‘Garbhapal Rasa’ is one among them. While screening through the texts it is observed that there are two formulations found in the name of ‘Garbhapal Rasa’ and both have different formula. Explanation of these two formulations is done here and there rasa panchanck with properties have been explained in this section. Discussion on the dosage and different anupana have been discussed here in this part from different texts. In which disease these rasa have been mentioned and in which condition have been mentioned here.  Depending on the properties and dosage and indication it is concluded that both the rasa can be used in the women because it is indicated in different diseased in pregnant women. So here is an attempt to compile the different references and discuss about the different aspects of formulation.

Ayurveda is an immortal and oldest time-tested depository of the medical assistance in the world. It is a growing healthcare industry worldwide and the global demand of the Ayurvedic drugs has been increased drastically in recent times. So, the quality and safe drug should be available for the market to meet the increasing demand. Hence there is need of quality control and standardization which starts right from the selection of raw drug. Raw drug identification and authentication is an important step in this process. Since ancient times a great emphasis given to identification of best quality raw drug before being used in a formulation. Ayurveda Acharyas have mentioned the characteristics of best raw drug. Grahyalakshana is suggesting the accepted quality of a drug and it is helpful in the selection of good quality raw drugs. As per many Rasashastra classics, the drugs are classified into various groups like Maharasa, uprasa, sadharan rasa etc. Sadharan rasa is a set of drugs which are used for rasasiddhi. Grahyalakshanas are very important in identifying the originality of the drug in raw form that eases human understanding. In present days, along with classical grahyagrahyatva; identification of minerals on the basis of geological parameters is also coupled. It will help in flawless selection of the ethical raw material.

Ayurveda is the oldest existing medical system which is getting importance globally. There are many branches of Ayurveda and one of them is Rasa Shastra and Bhaishajya Kalpana. Rasashastra is a branch of Ayurveda which deals with preparation of different formulations like herbal, mineral, and herbo-mineral.It is a process by which various metals, minerals and other substances including mercury are purified and combined with herbs in an attempt to treat illness. The formulations prepared out of herbs are called as kashthoushadhi and prepared out of mineral, metal, animal origin are called as Rasoushadhi. If the formulations are prepared out combination of both herbal and mineral/metal/animal are called as kashta-rasoushadhi (Herbo-mineral). Ramban rasa is one such formulation which is a herbo-mineral kharaliya rasayana which is used in different rogas like agnimandya and amavata. In different texts of rasa shastra there are 18 types of Rambana Rasa are available in the classics. Here is an attempt to compile all the references of Ramban rasa and discussed on the different aspects of formulation.

Different varieties of Drug are described by ancient Acharya’s for treatment and to maintain health of individual. Due to trade and impact of other culture in India many herbs from different part of world included in the flora of our continent. New immerging herb should be analyzed on all grounds of modern parameters. This gives a light on the proper way of treatment. Dhaula Phindawri is one such indigenous drug that is used in the management of urolithiasis but very few information has been mentioned by our Acharya. This creates a research area and to study the basic constituents of the drug, it was analyzed on various laboratorial test for doing its standardization.">

Diabetes mellitus is becoming a common metabolic disorder that has serious threat to public health in the world. There are chemicals and biochemical agent that helps in controlling diabetes but there is no permanent remedy available to be recovering completely from this disorder. Traditional Medicines derived from medicinal plants used by about 60% of the world’s population. Due to lesser side effect and low cost, the herbal formulations are becoming popular now a day particularly in curing the diseases. The traditional medicinal practitioners of various countries claim to cure diabetes or alleviate the major symptoms and progression of this disease through administration of medicinal plants. One of the etiologic factors implicated in the development of diabetes and its complications is the damage induced by free radicals and hence an anti-diabetic compound with antioxidant properties would be more beneficial. Tribal peoples, Borma, Sautal and Garo of five villages namely Rodgram, Kuchapara, Chalkpara, Uchadanga and Chandpukur under Shapahar Upozilla in Naogaon district were an indigenous community of northern region of Bangladesh, who still follow their traditional medicinal practices. Their traditional medicinal formulations contain a number of plants and plant parts, which they claim to be active anti-diabetic agents. In this research works, our interest was to find out the medicinal plants that the Tribal Practitioners use for treatment of diabetes. Literature review shows that almost all the plants used by the Bangladeshi tribal practitioners have reported antioxidantand anti-diabeticproperties. In this practical demonstration among tribal peoples with five medicinal plant extracts viz: (Allium sativum; Azadrirachta indica; Momordica charantia:  Ocimum sanctum and Trigonella foenum graecum) shows good results to improve the diabetes patients that have enormous potential for possible development of new and effective anti-diabetic’s modern drugs.

Bhaishajya Kalpana is an integral part of Ayurveda which deals with the processing methods of drugs and their various dosage forms. Sharkara kalpana (syrup) is one among secondary formulation prepared from the basic Panchvidha Kashaya Kalpana with the help of Sugar. Sharkara Kalpana came into existence in 20^th century in the context of Banapsha Sharkara in pittaj jwara by Acharya Krishnaram Bhatt and the reference of Sharkara also found in Dravyaguna Vigyaniyam Uttrarardha by Acharya Yadavji Trikamji.  An effort is made hereby to compile all the information related to Sharkara Kalpana including its definition, various references and chronicled appraisal. This paper also cover modern counterpart of Sharkara Kalpana i.e. Syrup including its importance, definition, classification, components, preparation and preservation of the same.