Currently Published Papers in Herbal Chemistry

Exploring the Anti-Inflammatory and Anticancer Activities of Curcumin-Free Turmeric Components: Insights into the Synergistic Effects of Turmeric's Bioactive Compounds

Nithya Selvaraj, Kanaga Palanisamy, Prema Rathinam, Senthilkumar Chelladurai, Premkumar Panneer Pandiyan , Chandrasekharan Padmanaban and Odaya Kumar Paramasivan,DOI: 10.24214/IJGHC/HC/14/1/01325

Turmeric (Curcuma longa) has been historically celebrated for its medicinal properties, with curcumin being the primary bioactive compound studied for its anti-inflammatory and anticancer effects. However, turmeric contains a diverse array of bioactive compounds that are not curcumin, which also contribute significantly to its therapeutic efficacy. This review explores the anti-inflammatory and anticancer activities of curcumin-free components, such as essential oils (turmerones), flavonoids (quercetin, kaempferol), and polysaccharides. Through a detailed examination of these compounds' molecular mechanisms and their synergistic effects, this review highlights the emerging therapeutic potential of curcumin-free turmeric constituents in treating chronic inflammatory diseases and cancer. Furthermore, clinical and preclinical evidence supports the idea that these bioactive compounds, particularly when combined, may have enhanced therapeutic effects over curcumin alone.

Influence of Geographical Variation in the hytochemistry of Adhatoda vasica leaves

Savitha Balan and Sreela R,DOI: 10.24214/IJGHC/HC/14/1/00612.

Adhatoda vasica (Vasa) leaf is a common bronchodialator in Ayurveda.  It has several quinazoline alkaloids which has high therapeutic values, especially, vasicine.  It also contains essential oils, vitamins, steroids and many fatty acids.  In this work an attempt was made to compare the effect of geographical variation in the Physico-chemical values of Adhatoda vasica leaves collected from different geographical regions of Trivandrum District, the capital of Kerala.  The study also extends to compare the quantity of vasicine content in these samples using HPTLC fingerprinting

The Role of the Mana in Multitasking and Its Physiological Impact in the Present Era

Dr. Aishwarya Pandey, and Prof. Ashok Kumar Sharma,DOI: 10.24214/IJGHC/HC/14/1/00105.

From day to day, everyone is too busy to Manage their lives. Hence, multitasking is a common practice involved by individuals in this era. It does save our time, but does it have any impact on health, whether psychologically or physically. From physiological prospectus one can understand the concept of Mana, the entity which makes the sensory organ  to connect with their respective stimulus or  motor  organ  to take action / regulates the action of Karmendriya. Manas is the connecting link between the Atma  with Sharir  and  hence influences  both.  Mana subtlety makes it move quickly and conjugate with the sense organs so quickly that it appears as though all sensory impressions are occurring concurrently at the same moment and that it is simultaneously connected to all Indriyas. Nevertheless, it only connects to one Indriya at a time. This demonstrates its Ekatva quality. Multitask is to work on two or more tasks at once, to switch between tasks often, or to complete several jobs quickly one after the other. Here by understanding the physiology of Mana, one can understand its role in multitasking and it’s physical and psychological effect on individual. As Mana has major a role in  keeping  healthy  status  as  well  as  in  disease production

Phytochemical and In-vitro Anti Diabetic Screening of Ethanolic and Aqueous Extract on Cleome gynandra Linn

Ravikumar V.R, Shri Shastikaa.S, Loganayagi. M, , Maheswari.V ,Natarajavel.R and Karishma.T. ,DOI: 10.24214/IJGHC/HC/13/4/13745

Preliminary phytochemical studies on ethanolic and aqueous extract  of whole plant of Cleome gynandra Linn (Cleomaceae) reveals the presence of Flavonoids, steroids, phenolic compounds, protein, carbohydrate, fixed oil and fat, gum and mucilage. Ethanolic and aqueous extract of whole plant of Cleome gynandra Linn were evaluated for  In-vitro Anti diabetic activity by inhibition of α- amylase and α-glycosidase enzymes respectively.  Leafs and roots of cleome gynandra  are used by tribal and traditional healers an antidiabetic drug. Although the hypoglycemic properties are not yet studied or proved cleome gynandra is believed to have the efficacy of lowering blood sugar. The results indicate that crude extracts exhibited significant anti-diabetic activity when compared to standard drug acarbose. The ethanolic extract shows moderately significant activity compare to aqueous extract of Cleome gynandra Linn

Morpho-Phytochemical and Antibacterial studies of immunity boosting Medicinal Plant Withania somnifera under various soil condition

Netra Pal Singh and Krishan Pratap Singh,DOI: 10.24214/IJGHC/HC/13/4/32836

Withania somnifera, also known as ashwagandha or winter cherry, has been an integral part of traditional medicine for centuries. This study aims to investigate the morpho-phytochemical and antibacterial properties of Withania somnifera, particularly focusing on how varying soil conditions and climatic factors in Agra influence its immune-boosting capabilities. Morphological studies showed improvements in plant height, flower, fruit, and seed parameters when grown in vermicompost. Notably, the shape and size of the roots were significantly enhanced in the vermicompost mixture. Phytochemical analysis of methanol extracts from the roots of Withania somnifera, cultivated under different soil conditions, confirmed the presence of alkaloids, glycosides, flavonoids, phenols, saponins, steroids, and tannins. Antibacterial testing of methanolic root extracts revealed effectiveness against pathogens such as E. coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis. These findings corroborate the traditional medicinal use of Withania somnifera for combating microbial infections, underscoring the potential of plant-based products as sources of antimicrobial agents